What is SARS-CoV-2 Neutralizing Antibody

What is Neutralizing Antibody?

A neutralizing antibody (NAb) is an antibody that defends a cell from a pathogen or infectious particle by neutralizing any effect it has biologically.

What is SARS-CoV-2 Neutralizing Antibody?

SARS-CoV-2 Neutralizing Antibody can block the interactions of spike protein with angiotensin-converting enzyme 2 (ACE2).

Infection with SARS-CoV-2 initiates an immune response, which includes the production of antibodies, or binding antibodies, in the blood. Not all binding antibodies can block cellular infiltration and replication of the SARS-CoV-2 virus. The subpopulation of the binding antibodies that can block cellular infiltration and replication of the virus are named neutralizing antibodies.

ACCU-TELL^® SARS-CoV-2 Neutralizing Antibody Cassette (Whole Blood/Serum/Plasma) is a rapid chromatographic immunoassay for the qualitative detection of neutralizing antibodies to SARS-CoV-2 in human whole blood, serum, or plasma as an aid in the diagnosis of the presence of neutralizing antibodies to SARS-CoV-2.